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10.1161/01.HYP.32.1.170 8
It belongs to a family of enzymes that catalyze the dismutation of the superoxide radical ( Cu/Zn SOD is a stable 15.9 kDa homodimer
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However, the reaction is kinetically driven in the forward direction by the removal of GS through the following reactions with thiolate anion (GS - ) and then with oxygen
In neurodegenerative conditions where fatty acid metabolism is impaired, the effective modulation of this pathway ensures efficient energy production from mitochondrial fatty acid oxidation [126]
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