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And this isn't a small risk

2016 | 1 page In Indiana, $7.25 an hour will not provide enough income for even a single adult to support themselves in any county

The complications may either be expressed by inadequate therapeutic delivery like in brain tumors, or by poor delivery of the drug across the BBB and ineffective bioavailability

Going straight to maintenance doses means tissue concentrations never reach therapeutic threshold

You're below therapeutic threshold
