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We also showed that activation of mitophagy results in hair regeneration in aged mice and skin organoid cultures

This resulted in improved potency and specificity on primary patient-derived GBM cell lines when compared to rucaparib alone ( Figure 5 , C4 ) ( 76)
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The synthesis of the diimidazolodiazepine DDX3X PROTAC degraders used in this study is outlined (Fig

Heat shock proteins (HSPs) are small molecular chaperones that serve in protein homeostasis and prevent protein aggregation and toxicity in conditions of cellular stress
Antibiotics-free medium were used throughout the transfection process
