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Furthermore, ROS-induced stimulation of ion channels and correlated K + deficit cause cell shrinkage and reduced viability, caspase-like activity as well as PCD [138]

Often referred to as the "master antioxidant," it plays a critical role in maintaining cellular health, detoxification, and overall well-being

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Day BJ (2004) Catalytic antioxidants: a radical approach to new therapeutics

However, their dysregulation can exacerbate inflammation and tissue damage in ARDS ( Given the central role of oxidative stress and lipid peroxidation in ARDS, targeting ferroptosis represents a promising therapeutic strategy ( 2 Ferroptosis in infection and ARDS development Cell death pathways play critical roles in immune homeostasis, infection defense, and inflammation resolution