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Multiple mechanisms are responsible for the anemia, but the main mechanisms are decreased RBC production due to suppression of erythropoiesis, reduced iron availability, and decreased RBC lifespan (extravascular hemolysis)
GS-ylation is implicated in the pathogenesis of IPF
doi: 10.1007/s10499-020-00556-7
It was also found that inhibition of the NF-B signaling pathway suppressed RANKL-induced osteoclast differentiation
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