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Hepatotoxicity and necrotic liver tissue damage following overdoses are due to reactive metabolites produced from APAP in the liver
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10.1007/s00702-007-0844-z J
In the second step, GSHS catalyzes the synthesis of another intermediate product, acylphosphate, at the C-terminal of the first intermediate -EC
Consequently, the inhibition of c-Met and TRK receptor kinases effectively suppresses the malignant phenotype of cancer cells
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