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Several classes of antidepressant drugs have been implicated in the serotonin syndrome, including serotonin reuptake inhibitors, tricyclic antidepressants, and monoamine oxidase inhibitors) [183,184]
Compounds that were selective toward the closely related APN and that exhibited sub-M affinity were identified
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(&alpha-MSH acts as a full agonist of all five melanocortin receptors)
Nature, 596 (7873), 583589
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