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The absence of SP-D in mice displayed iNOS-related chronic inflammation, alterations of surfactant homeostasis, and emphysematous changes
Ceglia et al., RNA neoantigen vaccines prime long-lived CD8 + T cells in pancreatic cancer
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It also serves to keep the hemoglobin iron in the ferrous state by reducing peroxides that undergo a reaction in which they extract an electron from ferrous iron, converting it to ferric iron, which impairs hemoglobin function
Moreover, global deletion of IGF-1 gene expression in mice does not result in glucose intolerance
