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The oxidative depletion of the eNOS cofactor BH 4 , deficiency in the eNOS substrate L-Arg or its analogue, accumulation of asymmetric dimethylarginine (ADMA) can result in eNOS uncoupling, leading to endothelial dysfunction and ultimately contributing to cardiovascular disease

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[DOI] [PubMed] [Google Scholar] 19.Li F., Chong Z

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Immunometabolism in the pathogenesis of vitiligo
