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The more direct published evidence currently available concerns VEGFR2 expression, VEGFR2-Akt-eNOS signaling, and Src-Cav-1-eNOS pathway activation rather than the complete transcriptional-to-secretory VEGF sequence

[PubMed] [Google Scholar] 172.Kodre V., Cemazar M., Pecar J., Sersa G., Cor A., Tozon N

JAGS 56(5):831-839

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Think of it as building new roads to bring supplies to a construction site