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N -Trimethyllysine hydroxylase The first enzyme of the L-carnitine biosynthetic pathway is N -trimethyllysine hydroxylase, an iron and 2-oxoglutarate (2OG)-dependent oxygenase that also requires ascorbate

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[19] [20] Patients taking anticoagulants should consult their GP or anticoagulation clinic before starting CoQ10 and have their INR monitored more frequently if supplementation begins

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