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If genuine tachyphylaxis is confirmed, strategies include dose escalation to the next tier, brief treatment breaks of 2 to 4 weeks to allow receptor resensitization, or switching to alternative GLP-1 agonists like semaglutide to provide different receptor activation patterns

The DLS measurements were carried out in triplicate, and the recorded values of the main with the standard deviation

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Start with moist heat therapy using a TMJ wrap, gentle jaw stretching devices like the gentle jaw, and massage techniques such as cork rolling or using the TMJAID Roller

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