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231 Canonical signaling pathways involved in liver repair and regeneration Signaling pathways play crucial roles in liver repair and regeneration, orchestrating key processes such as differentiation, proliferation, metabolism and cell death to maintain hepatic health and function
GSH as a regulator of growth and death In cell types such as lymphocytes and fibroblasts, an increased GSH level is associated with an early proliferative response and is essential for the cell to enter the S phase (Shaw and Chou, 1986

It is a useful reminder to consider vitamin B12 deficiency in people taking metformin who have megaloblastic anaemia, neuropathy or other symptoms suggestive of deficiency

However, obesity and insulin resistance (IR) are presently acknowledged as significant causative factors in MetS

Journal Of Affective Disorders