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Nuclear mitochondrial gene abnormalities were ruled-out using an oligonucleotide array with comparative genomic hybridization analysis that examines 180 nuclear genes involved in mitochondria function, including genes involved in fatty-acid oxidation, carnitine metabolism, mitochondrial biogenesis, mtDNA maintenance, transcription and translation, and ETC complex assembly (MitoMet, Baylor Medical Genetics Laboratory)

Am J Reprod Immunol 57:218226 Chung HW, Wen Y, Chun SH, Nezhat C, Woo BH, Lake Polan M (2001) Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-3 mRNA expression in ectopic and eutopic endometrium in women with endometriosis: a rationale for endometriotic invasiveness

There are also other supposed advantages in terms of cost of testing, amount of specimen needed to be tested, and the ability to evaluate both fresh and frozen specimens

Samir H, Mandour AS, Radwan F, Swelum AA, Nagaoka K, Sasaki K, Watanabe G

We have produced a large-scale computational biology analysis of the SNO-proteome in the cortex of Shank3 mutant mice (a popular model of ASD [171, 282, 283]) and found that among the NO-related molecular alterations, the most prominent change was the activation of the mTOR signaling pathway [171, 176]
