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For kinetic CYP3A4 activation and inhibition testing, ketoconazole or rifampicin (MilliporeSigma, catalog: R7382) was prepared at 2 final concentration in culture medium containing 2 luminogenic CYP substrate

Nat Rev Gastroenterol Hepatol 15: 2018

Untreated vascular risk factors, like high blood pressure, can accelerate the progression of dementia, especially Alzheimer's disease

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