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Copper is an essential cofactor for a range of enzymes involved in follicle function, including lysyl oxidase (involved in extracellular matrix cross-linking) and superoxide dismutase (an antioxidant enzyme expressed within the follicle)

KEAP1 E3 Ligase-Mediated Downregulation of NF-b Signaling by Targeting IKK

[DOI] [PMC free article] [PubMed] [Google Scholar] 253.Bernard K, and Thannickal VJ (2019)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Meredith MJ, Reed DJ

This leads to a gradual loss of vision, which can develop from visual disturbances such as spots and fogginess, to an almost complete loss of sight