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Frequency typically falls from three doses per week in weeks 14 to two in weeks 58

Evidence that the enzymes themselves can be modified by redox-related processes such as S -nitrosylation (Romero-Puertas and Sandalio 2016), in addition to the transcriptional control of the genes encoding them, emphasizes the intricacy of the checks and balances operating to maintain redox homeostasis within the cellular environment

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However, they are amongst Australias most common mineral deficiencies in sheep