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This phenomenon is thought to be due to the inability of cells to restore normal GSH levels or to increased production of reactive oxygen species (ROS), which can damage macromolecules fundamental to cell survival before being deactivated by antioxidant defenses

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doi: 10.1016/S0197-0186(00)00102-9

A: IGF-1 LR3 Injection must be administered subcutaneously or intramuscularly, strictly following the dosage prescribed by a qualified healthcare professional

The association of TGF-1 is seen with cardiac end points such as fibrosis and LVH is seen in other lysosomal storage diseases