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90 ROS overproduction is now recognized as a hallmark of IBD

270 In addition, a recent study showed that short-chain fatty acids can act as ligands of G-protein-coupled receptors (GPCRs), such as GPR41, GPR43, and GPR109A, to activate PKC that can in turn phosphorylate ZO-1 in order to increase intestinal barrier function

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Doctors can just as easily be blind to it in people even though B12 deficiency is a common health problem that affects an estimated 6% to 20% of the U.S
