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Aos, upon binding to cell-surface receptors on neurons, disrupt signal transduction, leading to a sustained interruption of intracellular Ca 2+ signaling through increased N-methyl-D-aspartate (NMDA) receptor-dependent Ca 2+ influx [77]

Compared with VLDL, IDL are relatively enriched in CE and depleted in TG

they are crossed by others parallel to the surface of the fovea

10.1021/cr4002287

Management of these pigmented lesions generally does not require intervention unless there is an aesthetic concern or a need to confirm the benign nature of the pigmentation

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