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Pharmacological inhibition of glutamine metabolism starves cells of nitrogen, abruptly stalling nucleotide synthesis [58]

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Nature (2007) 446:55761.10.1038/nature05698 54 ElliottDELiJBlumAMetwaliAQadirKUrbanJFJret alExposure to schistosome eggs protects mice from TNBS-induced colitis

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In PD, dopaminergic neurons, rich in PUFAs, experience extensive oxidative lipid damage, where dopamine metabolism itself generates ROS, fostering a ferroptotic environment, and ultimately lead to the degeneration of dopaminergic neurons (Ding X.-S

[111] targeted N-to-B delivery of thyrotropin-releasing hormone (TRH)(a polypeptide used for treating suicidal patients), using fast degrading poly(sebacic anhydride) (PSA) NPs
