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Severe hyperprolactinaemia is associated with decreased insulin binding in vitro and insulin resistance in vivo

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[70], the most frequently occurring adverse events included fever and chills, asthenia, transaminase level increase, nausea and skin toxicities

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Strides towards the development of multi-valent mRNA vaccines are being made each day, for example, a study by Awasthi and colleagues in mice and guinea pigs evaluated a trivalent mRNA LNP vaccine consisting of three different mRNAs encoding for HSV 2 surface glycoproteins shown to each elicit the same level of circulating antibodies when administered in combination as alone demonstrating increased breadth of protection from the combination of effects from each mRNA particle 19