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The GSH moiety of the drug has to be processed by GT before further processing by dipeptidases to generate dimethylarsino-cysteine (DMAC), a cysteine S -conjugate which is imported via cystine transporters ( Figure 4 )
Skeletal muscle then phosphorylates creatine to phosphocreatine (PCr) for rapid adenosine triphosphate (ATP) regeneration
10.1016/j.compbiomed.2022.105389 149 LiY.DouY.Da Veiga LeprevostF.GeffenY.CalinawanA
The number of animals assigned per condition was selected to account for the variability of the examined phenotypes based on pilot experiment and past experience with the animal models (6 animals per experimental condition)
They are not medicines and are not intended to treat, diagnose, mitigate, prevent, or cure diseases [124]
Perturbations in this axis influence vulnerability to oxidative stress (Di Marzo et al
