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As you can see, many people are at risk, but its believed that by far the largest cause of vitamin B12 deficiency is malabsorption

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Vitamin B 12 status in special populations The elderly Despite an apparent sufficient intake, vitamin B 12 deficiency is common among the elderly, and the prevalence is shown to increase with age (Allen, 2009
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This antioxidant function connects MOTS-c to the suppression of oxidative stress, one of the canonical drivers of biological aging

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