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Additionally, the enhancement of serine synthesis pathway in NRF2-addicted cancer cells (DeNicola et al

Iron accumulation within the cell can enhance the fenton reaction, generating more hydroxyl radicals and promoting lipid peroxidation, thereby facilitating ferroptosis

The non-specific regulation is hypothesized to involve the inhibition of NF-B activation, cyclooxygenase (COX) and prostaglandin synthesis

117 Martin-BastidaA.WardR

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