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They have identified specific cell surface markers and functional properties that distinguish Bregs from other B cell subsets, which helps in understanding their unique regulatory functions ( Establishing the existence of one or multiple subsets of Bregs has been challenging due to the absence of specific markers that are analogous to the Treg marker FoxP3 ( Specific markers for Bregs include (1)

J Pharmacol Exp Ther 1992

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Sulter G, Steen C, De Keyser J