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Our labs showed that supplementing macrophages from HIV positive patients with L-GSH led to a decrease in ROS production and improvement of macrophages ability to kill M.tb [74]

From the results of the survey, it appears the therapy is well tolerated with few reported side-effects

doi: 10.1186/s12943-024-02217-2 218 ChenLWenYXiongJChenYChenCB

In conclusion, while clinical translation is constrained by delivery, toxicity, and pharmacokinetic hurdles, ferritin-targeted approaches offer a novel and mechanistically rational avenue for treating aggressive brain cancers, warranting further preclinical optimization and early-phase clinical investigation

UPF additives induced depression The additives and flavoring compounds which are used in UPF production have been associated with a higher risk of depression (101)

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