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The synthesis of the neurotransmitters, such as dopamine, norepinephrine, histamine, and taurine, is B6-dependent (Kennedy, 2016

With cuprizone exposure, the recruitment of T-cells to the lesion site [70] may result from the decreased BBB integrity induced by cuprizone [75, 76] Cuprizone toxicity produces profound demyelination in the white and grey matter of the brain that mirrors sites of MS pathology [46]

5-Amino-1MQ contains a conjugated quinolinium ring system , giving it chemical properties very different from colourless peptide chains

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A number of other approaches have been proposed, most of which include minor modifications

The first trial was an investigator-initiated, randomized controlled study designed to evaluate the safety and efficacy of single-dose DPSC therapy, conducted at Beijing Stomatological Hospital from May 22, 2020, to February 16, 2023 (Ethical code: CMUSH-IRB-KJ-PJ-2019-14)