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In phase 3 trials, lecanemab and donanemab slowed clinical decline in early Alzheimers by roughly a quarter to a third over eighteen months, with a known risk of amyloid-related brain swelling and small bleeds

Cyclodextrins not only improve drug solubility and controlled release but also reduce toxicity and side effects, leading to safer and more effective treatments

Acute changes in short-term plasticity at synapses with elevated levels of neuronal calcium sensor-1

G., Testa R., Savarino V