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These effects are generally short-term

Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Zhao Y., Dai C., Wang Z., Chen W., Liu J., Zhuo R., Yu A., Huang S

While naturally produced in the liver, levels can decline with age, stress, and poor nutrition making supplementation beneficial for overall wellness
