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Ca 2+ is not metabolized and an overload of mitochondrial Ca 2+ may break down the electrochemical proton gradient resulting in a deficit of ATP followed by necrosis [89]
In addition to PNS, flavonoids and other substances in Panax notoginseng have a deep impact on immune regulation at multiple levels and play important roles in various types of inflammation (Yang C

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[DOI] [PMC free article] [PubMed] [Google Scholar] 256.Mirault ME
Inflamm Regen (2020) 40:37

it is not thought to have any other previously unknown risks or long-term effects
