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Moving forward, research should prioritize the integration of insights across preventative and therapeutic domains, fostering synergistic connections between diverse strategies to address these diseases with enhanced precision and efficacy, ultimately leading to improved diagnostic accuracy, treatment experiences, and sustained benefits for patients

Leonardi C, Matheson R, Zachariae C, Cameron G, Li L, Edson-Heredia E,

Liang H, Van Remmen H, Frohlich V, Lechleiter J, Richardson A, Ran Q.Gpx4 protects mitochondrial ATP generation against oxidative damage

Collectively, these findings suggest that targeting HADHA or SIRT1 may represent a potential therapeutic strategy for age-related HF

For instance, spermidine counteracted CAPs anti-tumor action by inducing transient G/G arrest in triple negative breast cancer cells, underscoring the need for biomarker-guided scheduling to avoid antioxidant interference in redox-based therapeutics [180]

G., Jaeger, V