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Targeted Inactivation of Copper Transporter Atp7b in Hepatocytes Causes Liver Steatosis and Obesity in Mice

95% CI 1.13.9) in men with low Gleason score [187] and failed to demonstrate any association with breast cancer risk in the American Cancer Society Cancer Prevention Study II Nutrition Cohort [111]

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In pre-symptomatic PD patients (e.g., those with RBD), this dysbiosis reduces short-chain fatty acid-producing bacteria, further elevating permeability and facilitating CNS infiltration of inflammatory mediators like LPS and -Syn (73)

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