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Through investigation of the full list of DEGs from the sam2/sam2 and sam1 11 /sam1 11 mutant strains, we were able to identify MET6, SAM1, SAM2, SAH1, CYS3, CYS4, STR3, STR2, GSH1, GPX2, and DUG1 of the glutathione biosynthesis pathway as showing altered expression

A statistically significant reduction in CDAI (Crohns disease activity index), NF-kB activity, and mucosal levels of the pro-inflammatory cytokine IL-1b was also observed [61]

In a separate study, we found that approximately 50% of F1 females were infertile

-KG formation can be catalyzed by either glutamate dehydrogenase (GDH) or aminotransferases

Some studies have shown a reduction in the catalase level compared with normal healthy controls [112, 113] In other studies, the catalase activity of erythrocytes from patients with vitiligo was not significantly different from that of healthy individuals [114, 115]

The genotoxic effects might be related to its ability to react with sulfhydryl groups and to induce oxidative damage [135]