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Drugs and thyroid function
These include altered choline metabolism, changes in neurotransmitter metabolism, defective DNA methylation with consequent poly (ADP-ribose) polymerase (PARP) overactivation and PARP-controlled cell death, excitotoxicity, up-regulation of re-entry to the cell division cycle, hypomethylation of myelin lipids and myelin basic protein, white matter changes, and the formation of homocysteine thiolactone and subsequent protein homocysteinylation (89)

doi: 10.1097/MD.0000000000034091, 65

[118] have reported that zinc concentrations are inversely associated with insulin resistance but not correlated with metabolic syndrome
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