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The Diabetes Prevention Program was a large, long-term study enrolling people with pre-diabetes, with one arm using metformin

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Both cyanocobalamin and other forms of cobalamin can trigger these reactions, and the risk appears higher with parenteral (injection) administration compared to oral supplementation Khatrawi2022Sajan2023Ullah2018+1 MORE

Administer with caution and keep treated animals under close observation

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