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The histological assessment used to investigate the healing parameters of the mice included edema, formation of blood vessels, retained follicles, formation of reticulin and collagen, number of inflammatory cells, and the number of subjects experiencing complete re-epithelialization

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Diabetes is a common comorbidity of COPD and patients with COPD are at increased risk of developing diabetes, while hyperglycemia can also reduce lung function and contribute to the progression and poor prognosis of COPD