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Pickart estimated the toxic dose at approximately 22,500 mg, which is over 11,000 times the recommended daily dose

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PMID: 86 LiangLYangCLiuLMaiGLiHWuLet al

Timing and Absorption Tips To maximize B12 absorption while breastfeeding: Take supplements with meals for better absorption Consider sublingual forms if you have absorption issues Space out doses if taking high amounts Balancing Multiple Supplements Many breastfeeding mothers take prenatal vitamins or other supplements

Nevertheless, these methodologies are associated with a high risk of infections, inflammation, high intracranial pressure, and damage to the brain tissue, and most of them are not suitable for chronic treatments [8,11]

Can Med Assoc J 1922;12:141-146