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A 2024 randomized controlled trial conducted by the National University of Singapore evaluated the effects of 100 mg of daily 5-HTP supplementation on older adults over a 12-week period

But three things limit what these animal studies can tell us

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A four-day study featuring curcumin assessed reduction of delayed onset muscle soreness and muscle damage in healthy adults following downhill running a standard muscle inflammation physical test, and certainly one that can test physical limits