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Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate

We finally purified the reaction mixture, that contained the enzyme and the other molecules, with cation exchange chromatography, by exploiting the positively charged N-trimethyl group to isolate HTML from the other negatively charged molecules such as ascorbate, 2-oxoglutarate, and succinate

Salehi B, Berkay Ylmaz Y, Antika G, Boyunegmez Tumer T, Fawzi Mahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N (2019) Insights on the use of -lipoic acid for therapeutic purposes

For example, thyroid hormone replacement should be taken at a consistent time relative to the ODT, preferably separated by at least one hour

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