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Conditions that can cause cobalamin deficiency include: Inflammatory bowel disease (IBD) Exocrine pancreatic insufficiency (EPI) Pancreatic cancer Chronic enteropathy Alimentary lymphoma Small intestinal dysbiosis Inherited selective cobalamin malabsorption Inherited selective cobalamin malabsorption, which is known as Imerslund-Grsbeck syndrome (IGS) in humans, makes a dog genetically predisposed to have difficulty absorbing cobalamin

Safety considerations, safety monitoring and AE reporting All AEs and serious adverse events (SAE) will be recorded by the study staff

Importantly, no adverse effects on insulin sensitivity were observed, confirming its safe metabolic profile in controlled studies

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Older adults might notice memory loss, trouble focusing, and brain fog. In serious cases, it can even lead to cognitive decline , making conditions like dementia worse