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Larger population studies would be needed to identify uncommon reactions

Sidrak S, Yoong T, Woolfenden S

Monoamine Oxidase A Gene Polymorphisms and Enzyme Activity Associated with Risk of Gout in Taiwan Aborigines. Human Genetics, vol
Enzymes associated with certain tumors can act on the peptide structure or ester bonds of nanocarrier to release the loaded drug at targeted site [46, 51]

Topical applications in clinical trials reported no irritation, sensitization, or adverse effects

Fact: Effects are reversible tone gradually returns toward baseline if you stop
