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Description
DN200434, an orally available inverse agonist of estrogen-related receptor (ERR), induces ferroptosis in sorafenib-resistant hepatocellular carcinoma (HCC) cells

The activation of endothelial TRPV4 (transient receptor potential vanilloid 4) channels facilitates vasodilation through the influx of Ca 2 + and the stimulation of inositol 1,4,5-trisphosphate receptors that release Ca 2 + from the endoplasmic reticulum [60]

doi: 10.3748/wjg.v20.i25.8082 66
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This enables cancer cells to evade the inflammatory response typically associated with pyroptosis

doi: 10.1001/archopht.1968.03850040425011

2005a;391:567574
