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It is suggested that induction of iNOS in response to ROS causes peroxynitrite-mediated damage to OPA1, sequentially leading to mitochondrial fragmentation, cytochrome c release and subsequent apoptosis (Di Meo et al., 2016)

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[DOI] [PubMed] [Google Scholar] 92.Ritchie K.J., Walsh S., Sansom O.J., Henderson C.J., Wolf C.R

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In the present study, we aimed to investigate how age-related changes in metabolite levels contribute to AD pathology, with a specific focus on the role of palmitoyl-L-carnitine

doi: 10.3390/molecules26237407 156 ZhaiZ.ZhangX.DingY.HuangZ.LiQ.ZhengM.et al