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Description
The ARE regulator is activated by Nrf2 transcription factors
[DOI] [PubMed] [Google Scholar] 15.Brodsky V.Y., Khavinson V.K., Zolotarev Y.A., Nechaeva N.N., Malinin V.V., Novikova T.E., Gvazava I.G., Fateeva V.I

(Kato et al., 2022) As the mucins are secreted and insufficiently hydrated, the viscosity and elasticity of the mucus increase and make mucociliary and cough clearance more difficult (Tambascio et al., 2013

An invasive approach includes delivery of medication directly to the brain through injection/surgical implants or disruption of the tight endothelial junction of the BBB to facilitate drug penetration

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