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It should be taken in consideration that different profiles have been reported for macrocyclic GBCAs

First synthesis of racemic trans Propargylamino-Donepezil, a Pleiotrope agent able to both inhibit AChE and MAO-B, with potential interest against Alzheimer's disease

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SELENOP per se was reported to be in oxidized form for the uptake to take place (Shetty et al., 2018)

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Perrella et al., 2020)