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Low levels of artificial light at night (5 lux) disrupt circadian rhythmicity with a reduction in Per1 and Per2 expression in the SCN, concurrent with altered expression of Bmal1, Per1, Per2 , and Cry1 in the liver of mice ( Night Shift Work, Travel, and Social Jet Lag Coinciding with the increase in light pollution as a result of industrialization, current society has deviated from 9 to 5 workdays

Applications include investigating sleep-aging connections and therapeutic approaches for circadian rhythm disorders

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10.1038/srep09102 335 ZhuC.LiJ.LiuC.ZhouP.YangH.LiB