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Elderly patients need prolonged barrier ointment use to prevent rapid relapses

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Studies using radiolabeled MT-2 show hypothalamic concentrations remain elevated for 68 hours post-injection, which explains why a single morning dose produces appetite suppression lasting through the evening meal

Indeed, the induction was not observed neither in fed, nor in starved kin-2 mutant animals (Figure 6E), excluding the transcriptional and post-transcriptional regulation of atgl-1