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It's tart

140 Mice lacking SIRT3 become more sensitive to the stimulation of several pharmacological or non-pharmacological stressors, showing symptoms, such as fibrosis, cardiac hypertrophy and high mortality

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Metabolism and Pharmacokinetics (Panel 2) : The drug operates with a rapid 3 to 5 minute half-life, which translates to a short clinical duration of approximately 6 to 10 minutes

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