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The human brain and central nervous system (CNS) are notoriously complex, operating through a huge network of neurons that communicate with each other using chemical messengers, or neurotransmitters
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The bottom of subpocket C in proximity to the chimera ligand contained several mostly non-polar (purple) probes with positive free energy values, indicating that it may be filled with additional non-polar substituents

Aged animals typically exhibit difficulty with spatial learning tasks, yet Dihexa treatment enabled these older rats to perform at levels comparable to young animals, suggesting the compound's capacity to restore age-compromised cognitive function

Modern pharmacological studies have revealed that Prunella possesses antioxidant, immunoregulatory, anti-inflammatory, and antiaging functions [75,76]
